Introduction and Application

Anhydrous calcium hydrogen phosphate can be used as an excipient or as a calcium supplement. It is non-hygroscopic, stable at room temperature, and will not be hydrated into dihydrate.

Coarse particles of anhydrous calcium hydrogen phosphate have good compressibility and fluidity. When used in pharmaceutical preparations, its deformation mechanism is brittle fracture, which reduces its strain sensitivity. Unlike dihydrogen calcium phosphate dihydrate, it may experience delamination and capping when tableting under high pressure. This phenomenon is clearly observed when tableting with a deep concave punch when its dosage accounts for most of the prescription. This phenomenon has nothing to do with the degree of compression.

Different particle sizes of anhydrous calcium hydrogen phosphate can be used in different formulation processes. Small particle sizes can be used in classic wet granulation, and coarser particles can be used for direct tableting.

Mainly used as a diluent for tablets and capsules.

Specification 

Packaging and storage

Externally use composite paper bags or cardboard barrels, lined with high-pressure polyethylene film bags, 25 kg/bag, or can be packaged according to customer agreement.