Tris(hydroxymethyl)aminomethane (TRIS) CAS 77-86-1
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Product Details
Introduction to Tris(hydroxymethyl)aminomethane (TRIS) CAS 77-86-1:
Other Names: Trometamol, 8VTE 1L; Tham-E, Thamset, THAM, Riladyl, Talatrol, 1,3-Propanediol, 2-amino-2-(hydroxymethyl); Trizma; TRISMAT; TRIS; Tromethamine/Pehanorm
Tris(hydroxymethyl)aminomethane, a white crystalline solid or powder, has a melting point of 171–172°C and a boiling point of 219–220°C at 1.3 kPa. It is soluble in ethanol and water, slightly soluble in ethyl acetate and benzene, and insoluble in diethyl ether and carbon tetrachloride. It is corrosive to copper and aluminum and is irritating.
Tris(hydroxymethyl)aminomethane is a non-sodium amino buffer. In body fluids, it reacts with water, thereby reducing its concentration. It is suitable for treating both metabolic acidosis and respiratory acidosis and is an ideal medication for patients with metabolic acidosis complicated by acute respiratory acidosis.
Tris(hydroxymethyl)aminomethane, commonly known as Tris, is widely used as a solvent for nucleic acids and proteins and is also used as a titration standard.
Tris(hydroxymethyl)aminomethane (TRIS) CAS 77-86-1 Specifications
Appearance | White crystal powder |
Content | ≥99.9% |
PH range | 7.0-9.1 |
pKa | 8.1 |
Melting point | 168-172ºC |
Solubility | Soluble in ethanol and water |
Tris(hydroxymethyl)aminomethane (TRIS) CAS 77-86-1 Applications:
1.) Tris(hydroxymethyl)aminomethane is an important biological buffer with a buffer range of 7.0~9.0. It is widely used in the preparation of buffers in biochemistry, molecular biology, and other fields. It can also be used in the preparation of in vitro diagnostic reagents.
2.) Tris(hydroxymethyl)aminomethane is an important pharmaceutical intermediate that can be used to synthesize drugs such as dextrorotatory tromethamine, ketorolac tromethamine, fosfomycin tromethamine, and carboprost tromethamine.
3.) Tris(hydroxymethyl)aminomethane can be used as a pharmaceutical adjuvant in contrast agents, biological preparations, oral grade, eye drops and other preparations.
4.) Tris(hydroxymethyl)aminomethane is widely used as a solvent for nucleic acids and proteins.
5.) Tris(hydroxymethyl)aminomethane can also be used in the fields of pH regulators, vulcanization accelerators, cosmetics (agents, lotions), mineral oils, paraffin emulsifiers, and activated carbon absorbents.

Package:
25kg/drum or as required
Keyword:
Tris(hydroxymethyl)aminomethane
TRIS
CAS 77-86-1
Trometamol
Tromethamine/Pehanorm
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