What Is Dimethyl Adipate?

2026-07-29

Dimethyl adipate (DMA) is a colourless, transparent liquid with the chemical formula C₈H₁₄O₄, CAS No. 627-93-0, molecular weight 174.19, density 1.062 g/cm³ (20°C), melting point 8°C, boiling point 109–110°C (14 mmHg) or 228.7°C (760 mmHg), and flash point 107.2°C. It is insoluble in water but soluble in alcohols and ethers; its refractive index is 1.428 (20°C). It is classified as a low-toxicity substance and is used industrially as a synthetic intermediate and a raw material for pharmaceuticals and fragrances. It also serves as a plasticiser and a high-boiling-point solvent and is used in the production of 1,6-hexanediol and as a standard substance for gas chromatography. It should be stored in a cool, dry place in a sealed container, away from oxidising agents, acids, and bases.

Dimethyl Adipate Properties

Melting point	8°C (lit.)
Boiling point	109-110 °C/14 mmHg (lit.)
Density	1.062 g/mL at 20 °C (lit.)
vapor pressure	0.2 mm Hg (20°C)
refractive index	0.2 mm Hg (20°C)
Flash point	225 °F
storage temp.	Store below +30°C.
Odor	at 100.00 %. mild nutty
Water Solubility	Miscible with alcohols and ether. Immiscible with water.
InChI	1S/C8H14O₄/c1-11-7(9)5-3-4-6-8(10)12-2/h3-6H₂,1-2H₃
InChIKey	UDSFAEKRVUSQDD-UHFFFAOYSA-N

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Safety Information

Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P280-P261
PPE	Eyeshields, Gloves
Safety Statements	24/25
Autoignition Temperature	680 °F
RTECS	AV1645000
Storage Class	10 - Combustible liquids

What Is Dimethyl Adipate Used For?

Dimethyl adipate can be used as a raw material for synthetic intermediates, pharmaceuticals, and fragrances; as a plasticiser and high-boiling-point solvent; as the main component of dimethyl nylonate; as a raw material for the hydrogenation of 1,6-hexanediol; and as a standard substance for gas chromatography.